L23V (p.Leu23Val) variant of ETS1 (Protein C-ets-1)
L23V (p.Leu23Val) in ETS1 (Protein C-ets-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, experimental measurements, and structural context.
L23V (p.Leu23Val) variant details
- p.Leu23Val
- cosmic curated COSV10440
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- MetaLR 0.05
- MetaSVM -1.00
- CADD 21.30
- SIFT 0.33
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available
- ETS1 Pointed domain domainome 1.0: score -0.955