L23F (p.Leu23Phe) variant of ETS1 (Protein C-ets-1)
L23F (p.Leu23Phe) in ETS1 (Protein C-ets-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, experimental measurements, and structural context.
L23F (p.Leu23Phe) variant details
- p.Leu23Phe
- cosmic curated COSV60094
- gnomAD rs1202062176
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- MetaLR 0.08
- MetaSVM -1.07
- CADD 21.60
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- ETS1 Pointed domain domainome 1.0: score -0.955