I226S (p.Ile226Ser) variant of ETS1 (Protein C-ets-1)
I226S (p.Ile226Ser) in ETS1 (Protein C-ets-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
I226S (p.Ile226Ser) variant details
- p.Ile226Ser
- gnomAD 11-128484981-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.28
- MetaLR 0.12
- MetaSVM -1.03
- CADD 23.90
- PolyPhen-2 0.39
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available