S10Y (p.Ser10Tyr) variant of ESR1 (Estrogen receptor)
S10Y (p.Ser10Tyr) in ESR1 (Estrogen receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
S10Y (p.Ser10Tyr) variant details
- p.Ser10Tyr
- gnomAD 6-151807941-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.51
- MetaLR 0.83
- MetaSVM 0.79
- CADD 24.40
- PolyPhen-2 0.80
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available