L23L (p.Leu23Leu) variant of ESR1 (Estrogen receptor)
L23L (p.Leu23Leu) in ESR1 (Estrogen receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
L23L (p.Leu23Leu) variant details
- p.Leu23Leu
- rs1399427744
- gnomAD 6-151807979-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.501
- CADD 14.10
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available
- Literature evidence available