W34C (p.Trp34Cys) variant of ERCC5 (P28715)
W34C (p.Trp34Cys) in ERCC5 (P28715) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
W34C (p.Trp34Cys) variant details
- p.Trp34Cys
- cosmic curated COSV63245
- ESP rs373207563
- ExAC rs373207563
- TOPMed rs373207563
- Missense
- Variant Prioritization Score for Impact Estimate 0.84
- CADD 33.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available