T57S (p.Thr57Ser) variant of ERCC5 (P28715)
T57S (p.Thr57Ser) in ERCC5 (P28715) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
T57S (p.Thr57Ser) variant details
- p.Thr57Ser
- TOPMed rs924662120
- Missense
- Variant Prioritization Score for Impact Estimate 0.628
- CADD 25.40
- PolyPhen-2 0.55
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available