R61W (p.Arg61Trp) variant of ERCC5 (P28715)
R61W (p.Arg61Trp) in ERCC5 (P28715) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
R61W (p.Arg61Trp) variant details
- p.Arg61Trp
- gnomAD rs1439118079
- Missense
- Variant Prioritization Score for Impact Estimate 0.837
- CADD 32.00
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available