L24M (p.Leu24Met) variant of ERCC4 (DNA repair endonuclease XPF)
L24M (p.Leu24Met) in ERCC4 (DNA repair endonuclease XPF) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L24M (p.Leu24Met) variant details
- p.Leu24Met
- gnomAD rs1225226851
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.39
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available