E25G (p.Glu25Gly) variant of ERCC4 (DNA repair endonuclease XPF)
E25G (p.Glu25Gly) in ERCC4 (DNA repair endonuclease XPF) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
E25G (p.Glu25Gly) variant details
- p.Glu25Gly
- gnomAD 16-13920239-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.13
- CADD 26.50
- PolyPhen-2 0.29
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available