E19K (p.Glu19Lys) variant of ERCC4 (DNA repair endonuclease XPF)

E19K (p.Glu19Lys) in ERCC4 (DNA repair endonuclease XPF) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of XFE progeroid syndrome. The record also includes structural context.

E19K (p.Glu19Lys) variant details