M65T (p.Met65Thr) variant of ERCC3 (P19447)
M65T (p.Met65Thr) in ERCC3 (P19447) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
M65T (p.Met65Thr) variant details
- p.Met65Thr
- gnomAD rs1685352525
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.63
- ESM-1b 0.00
- AlphaMissense 0.80
- CADD 24.50
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available