E87G (p.Glu87Gly) variant of ERCC3 (P19447)
E87G (p.Glu87Gly) in ERCC3 (P19447) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
E87G (p.Glu87Gly) variant details
- p.Glu87Gly
- ExAC rs773655670
- gnomAD rs773655670
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.89
- ESM-1b 1.00
- AlphaMissense 0.98
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available