E22G (p.Glu22Gly) variant of ERCC3 (P19447)
E22G (p.Glu22Gly) in ERCC3 (P19447) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
E22G (p.Glu22Gly) variant details
- p.Glu22Gly
- ExAC rs756471066
- TOPMed rs756471066
- gnomAD rs756471066
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.15
- ESM-1b 0.29
- AlphaMissense 0.10
- CADD 23.90
- PolyPhen-2 0.02
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 3e-05)
- Structural context available