A37V (p.Ala37Val) variant of ERCC3 (P19447)
A37V (p.Ala37Val) in ERCC3 (P19447) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
A37V (p.Ala37Val) variant details
- p.Ala37Val
- gnomAD rs1435070019
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.28
- ESM-1b 0.00
- AlphaMissense 0.11
- CADD 22.80
- PolyPhen-2 0.17
- SIFT 0.44
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available