V20L (p.Val20Leu) variant of ERBB4 (Q15303)
V20L (p.Val20Leu) in ERBB4 (Q15303) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
V20L (p.Val20Leu) variant details
- p.Val20Leu
- ESP rs373308672
- ExAC rs373308672
- TOPMed rs373308672
- gnomAD rs373308672
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.15
- CADD 19.20
- PolyPhen-2 0.01
- SIFT 0.72
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available