V15L (p.Val15Leu) variant of ERBB4 (Q15303)
V15L (p.Val15Leu) in ERBB4 (Q15303) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V15L (p.Val15Leu) variant details
- p.Val15Leu
- ExAC rs751515664
- TOPMed rs751515664
- gnomAD rs751515664
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.16
- CADD 7.07
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 0.00013)
- Structural context available