V9L (p.Val9Leu) variant of ERBB3 (P21860)
V9L (p.Val9Leu) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
V9L (p.Val9Leu) variant details
- p.Val9Leu
- TOPMed rs933549006
- gnomAD rs933549006
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.07
- MetaLR 0.19
- MetaSVM -0.80
- CADD 24.10
- PolyPhen-2 0.06
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available