V58M (p.Val58Met) variant of ERBB3 (P21860)
V58M (p.Val58Met) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
V58M (p.Val58Met) variant details
- p.Val58Met
- ExAC rs750947241
- TOPMed rs750947241
- gnomAD rs750947241
- Missense
- Variant Prioritization Score for Impact Estimate 0.697
- REVEL 0.62
- MetaLR 0.76
- MetaSVM 0.66
- CADD 25.40
- PolyPhen-2 0.75
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available