V28L (p.Val28Leu) variant of ERBB3 (P21860)
V28L (p.Val28Leu) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
V28L (p.Val28Leu) variant details
- p.Val28Leu
- gnomAD 12-56080382-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.13
- MetaLR 0.42
- MetaSVM -0.30
- CADD 35.00
- PolyPhen-2 0.01
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available