V22E (p.Val22Glu) variant of ERBB3 (P21860)
V22E (p.Val22Glu) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
V22E (p.Val22Glu) variant details
- p.Val22Glu
- gnomAD rs1868338618
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.13
- MetaLR 0.20
- MetaSVM -0.72
- CADD 23.50
- PolyPhen-2 0.01
- SIFT 0.78
- Most common in the HGDP:BRAHUI population (allele frequency 0.022)
- Structural context available