V22A (p.Val22Ala) variant of ERBB3 (P21860)
V22A (p.Val22Ala) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
V22A (p.Val22Ala) variant details
- p.Val22Ala
- gnomAD 12-56080365-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.15
- MetaLR 0.17
- MetaSVM -0.79
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available