T39A (p.Thr39Ala) variant of ERBB3 (P21860)
T39A (p.Thr39Ala) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
T39A (p.Thr39Ala) variant details
- p.Thr39Ala
- Ensembl rs750029748
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.18
- MetaLR 0.36
- MetaSVM -0.52
- CADD 20.30
- PolyPhen-2 0.01
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available