S25Y (p.Ser25Tyr) variant of ERBB3 (P21860)
S25Y (p.Ser25Tyr) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
S25Y (p.Ser25Tyr) variant details
- p.Ser25Tyr
- gnomAD 12-56080374-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.20
- MetaLR 0.32
- MetaSVM -0.39
- CADD 22.70
- PolyPhen-2 0.07
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available