S25P (p.Ser25Pro) variant of ERBB3 (P21860)
S25P (p.Ser25Pro) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
S25P (p.Ser25Pro) variant details
- p.Ser25Pro
- gnomAD 12-56080373-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.18
- MetaLR 0.38
- MetaSVM -0.22
- CADD 23.30
- PolyPhen-2 0.01
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available