S20P (p.Ser20Pro) variant of ERBB3 (P21860)
S20P (p.Ser20Pro) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
S20P (p.Ser20Pro) variant details
- p.Ser20Pro
- Ensembl rs2136781481
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.21
- MetaLR 0.22
- MetaSVM -0.55
- CADD 23.80
- PolyPhen-2 0.33
- SIFT 0.38
- Population evidence available
- Structural context available