S15R (p.Ser15Arg) variant of ERBB3 (P21860)
S15R (p.Ser15Arg) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
S15R (p.Ser15Arg) variant details
- p.Ser15Arg
- gnomAD 12-56080345-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.15
- MetaLR 0.21
- MetaSVM -0.81
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available