R55W (p.Arg55Trp) variant of ERBB3 (P21860)
R55W (p.Arg55Trp) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R55W (p.Arg55Trp) variant details
- p.Arg55Trp
- ExAC rs781661153
- TOPMed rs781661153
- gnomAD rs781661153
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.24
- MetaLR 0.35
- MetaSVM -0.65
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available