R55G (p.Arg55Gly) variant of ERBB3 (P21860)
R55G (p.Arg55Gly) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
R55G (p.Arg55Gly) variant details
- p.Arg55Gly
- ExAC rs781661153
- TOPMed rs781661153
- gnomAD rs781661153
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.19
- MetaLR 0.14
- MetaSVM -0.97
- CADD 12.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available