R2W (p.Arg2Trp) variant of ERBB3 (P21860)
R2W (p.Arg2Trp) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
R2W (p.Arg2Trp) variant details
- p.Arg2Trp
- gnomAD 12-56080304-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.21
- CADD 25.60
- PolyPhen-2 0.32
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available