R2S (p.Arg2Ser) variant of ERBB3 (P21860)
R2S (p.Arg2Ser) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
R2S (p.Arg2Ser) variant details
- p.Arg2Ser
- gnomAD 12-56080306-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.09
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available