R18W (p.Arg18Trp) variant of ERBB3 (P21860)
R18W (p.Arg18Trp) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
R18W (p.Arg18Trp) variant details
- p.Arg18Trp
- gnomAD 12-56080352-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.15
- MetaLR 0.39
- MetaSVM -0.35
- CADD 23.90
- PolyPhen-2 0.40
- SIFT 0.25
- Population evidence available
- Structural context available
- Literature evidence available