R18Q (p.Arg18Gln) variant of ERBB3 (P21860)
R18Q (p.Arg18Gln) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R18Q (p.Arg18Gln) variant details
- p.Arg18Gln
- TOPMed rs1317504479
- gnomAD rs1317504479
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.04
- MetaLR 0.19
- MetaSVM -0.90
- CADD 21.20
- PolyPhen-2 0.00
- SIFT 0.55
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available