R18G (p.Arg18Gly) variant of ERBB3 (P21860)
R18G (p.Arg18Gly) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
R18G (p.Arg18Gly) variant details
- p.Arg18Gly
- gnomAD 12-56080352-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.17
- MetaLR 0.23
- MetaSVM -0.80
- CADD 23.00
- PolyPhen-2 0.01
- SIFT 0.50
- Population evidence available
- Structural context available
- Literature evidence available