Q8L (p.Gln8Leu) variant of ERBB3 (P21860)
Q8L (p.Gln8Leu) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Q8L (p.Gln8Leu) variant details
- p.Gln8Leu
- gnomAD 12-56080323-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.21
- MetaLR 0.10
- MetaSVM -0.79
- CADD 24.30
- PolyPhen-2 0.07
- SIFT 0.65
- Population evidence available
- Structural context available
- Literature evidence available