L7M (p.Leu7Met) variant of ERBB3 (P21860)
L7M (p.Leu7Met) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L7M (p.Leu7Met) variant details
- p.Leu7Met
- gnomAD 12-56080319-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.18
- MetaLR 0.49
- MetaSVM 0.05
- CADD 24.60
- PolyPhen-2 0.99
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available