L16P (p.Leu16Pro) variant of ERBB3 (P21860)
L16P (p.Leu16Pro) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
L16P (p.Leu16Pro) variant details
- p.Leu16Pro
- gnomAD 12-56080347-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.33
- MetaLR 0.42
- MetaSVM -0.17
- CADD 25.10
- PolyPhen-2 0.31
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available