L16M (p.Leu16Met) variant of ERBB3 (P21860)
L16M (p.Leu16Met) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L16M (p.Leu16Met) variant details
- p.Leu16Met
- gnomAD 12-56080346-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.17
- MetaLR 0.44
- MetaSVM -0.31
- CADD 24.30
- PolyPhen-2 0.53
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available