L13R (p.Leu13Arg) variant of ERBB3 (P21860)
L13R (p.Leu13Arg) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
L13R (p.Leu13Arg) variant details
- p.Leu13Arg
- gnomAD 12-56080338-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.30
- MetaLR 0.49
- MetaSVM 0.01
- CADD 26.20
- PolyPhen-2 0.09
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available