L12F (p.Leu12Phe) variant of ERBB3 (P21860)
L12F (p.Leu12Phe) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
L12F (p.Leu12Phe) variant details
- p.Leu12Phe
- gnomAD 12-56080336-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.06
- MetaLR 0.24
- MetaSVM -0.93
- CADD 16.30
- PolyPhen-2 0.00
- SIFT 0.99
- Population evidence available
- Structural context available
- Literature evidence available