L10P (p.Leu10Pro) variant of ERBB3 (P21860)
L10P (p.Leu10Pro) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
L10P (p.Leu10Pro) variant details
- p.Leu10Pro
- gnomAD 12-56080329-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.30
- MetaLR 0.43
- MetaSVM -0.10
- CADD 30.00
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available