G61R (p.Gly61Arg) variant of ERBB3 (P21860)
G61R (p.Gly61Arg) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.88 / 1. The record also includes population frequency data and structural context.
G61R (p.Gly61Arg) variant details
- p.Gly61Arg
- ExAC rs749691155
- TOPMed rs749691155
- gnomAD rs749691155
- Missense
- Variant Prioritization Score for Impact Estimate 0.879
- REVEL 0.93
- MetaLR 0.89
- MetaSVM 0.99
- CADD 28.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available