G23S (p.Gly23Ser) variant of ERBB3 (P21860)
G23S (p.Gly23Ser) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
G23S (p.Gly23Ser) variant details
- p.Gly23Ser
- gnomAD rs1868338662
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.12
- MetaLR 0.20
- MetaSVM -0.80
- CADD 23.40
- PolyPhen-2 0.04
- SIFT 0.72
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available