G23D (p.Gly23Asp) variant of ERBB3 (P21860)
G23D (p.Gly23Asp) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G23D (p.Gly23Asp) variant details
- p.Gly23Asp
- gnomAD rs1868338709
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.14
- MetaLR 0.24
- MetaSVM -0.74
- CADD 23.30
- PolyPhen-2 0.06
- SIFT 0.41
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available