G23C (p.Gly23Cys) variant of ERBB3 (P21860)
G23C (p.Gly23Cys) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
G23C (p.Gly23Cys) variant details
- p.Gly23Cys
- gnomAD 12-56080367-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.14
- MetaLR 0.45
- MetaSVM -0.20
- CADD 31.00
- PolyPhen-2 0.79
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available