G19S (p.Gly19Ser) variant of ERBB3 (P21860)
G19S (p.Gly19Ser) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G19S (p.Gly19Ser) variant details
- p.Gly19Ser
- cosmic curated COSV10725
- ExAC rs748811895
- gnomAD rs748811895
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.07
- MetaLR 0.11
- MetaSVM -0.89
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.75
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available