G19D (p.Gly19Asp) variant of ERBB3 (P21860)
G19D (p.Gly19Asp) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
G19D (p.Gly19Asp) variant details
- p.Gly19Asp
- gnomAD 12-56080356-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.14
- MetaLR 0.19
- MetaSVM -0.77
- CADD 22.50
- PolyPhen-2 0.02
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available