G19C (p.Gly19Cys) variant of ERBB3 (P21860)
G19C (p.Gly19Cys) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
G19C (p.Gly19Cys) variant details
- p.Gly19Cys
- gnomAD 12-56080355-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.14
- MetaLR 0.29
- MetaSVM -0.57
- CADD 23.60
- PolyPhen-2 0.24
- SIFT 0.37
- Population evidence available
- Structural context available
- Literature evidence available