G11V (p.Gly11Val) variant of ERBB3 (P21860)
G11V (p.Gly11Val) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G11V (p.Gly11Val) variant details
- p.Gly11Val
- gnomAD rs1287546945
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.19
- MetaLR 0.19
- MetaSVM -0.89
- CADD 22.50
- PolyPhen-2 0.05
- SIFT 0.52
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available