G11S (p.Gly11Ser) variant of ERBB3 (P21860)
G11S (p.Gly11Ser) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G11S (p.Gly11Ser) variant details
- p.Gly11Ser
- gnomAD rs1868337864
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.14
- MetaLR 0.19
- MetaSVM -0.78
- CADD 22.20
- PolyPhen-2 0.03
- SIFT 0.42
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available